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・ 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase
3alpha,7alpha,12alpha-trihydroxycholestan-26-al 26-oxidoreductase
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3alpha,7alpha,12alpha-trihydroxycholestan-26-al 26-oxidoreductase : ウィキペディア英語版
3alpha,7alpha,12alpha-trihydroxycholestan-26-al 26-oxidoreductase

In enzymology, a 3alpha,7alpha,12alpha-trihydroxycholestan-26-al 26-oxidoreductase is an enzyme that catalyzes the chemical reaction:
:(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + NAD+ + H2O \rightleftharpoons (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + NADH + 2 H+
The 3 substrates of this enzyme are (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al, NAD+, and H2O, whereas its 2 products are (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate, NADH, and H+. This enzyme participates in bile acid biosynthesis.
== Nomenclature ==

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al:NAD+ 26-oxidoreductase. Other names in common use include:
* cholestanetriol-26-al 26-dehydrogenase,
* 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al, dehydrogenase,
* trihydroxydeoxycoprostanal dehydrogenase,
* THAL-NAD oxidoreductase,
* 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al:NAD+, and
* 26-oxidoreductase.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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